01 · 1973
GHK-Cu
United States
Copper-binding tripeptide with laboratory and limited topical human evidence.
Open the individual record →Pilgrims
Experimental or regionally used compounds still traveling through evidence
02 · 1990s
BPC-157
Zagreb, Croatia
Mostly animal and laboratory evidence; no FDA-approved use.
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03 · 1980s lineage
TB-500
United States / unclear commercial origin
Marketed thymosin-β4 fragment with uncertain product identity and limited human evidence.
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04 · 2000s
CJC-1295
Individual molecule · investigationalMontreal, Canada
An experimental long-acting growth-hormone-releasing hormone analog.
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05 · 1998
Ipamorelin
Individual molecule · investigationalDenmark
An experimental growth-hormone secretagogue and ghrelin-receptor agonist.
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06 · 1980s–1991
Semax
Moscow, Russia
ACTH-fragment analog used in Russia; not FDA-approved and independently validated evidence is limited.
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07 · 1990s–2000s
Selank
Moscow, Russia
Tuftsin analog used for anxiety-related indications in Russia; not FDA-approved.
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08 · approved 1990; discontinued 2008
Sermorelin
United States
GHRH(1-29) with historical U.S. approvals for diagnosis and pediatric growth failure; the Geref products were later discontinued.
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09 · 1970s
Thymosin alpha-1
Washington, D.C., USA
Immune-modulating thymic peptide approved in some countries, not by FDA in the United States.
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10 · 2015
MOTS-c
Los Angeles, USA
Mitochondrial-derived peptide with intriguing metabolic biology but no approved therapeutic use.
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11 · α-MSH fragment
KPV
Research lineage
Anti-inflammatory tripeptide studied mainly in preclinical models.
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12 · 1980s–1990s
Epitalon
St. Petersburg, Russia
Synthetic tetrapeptide associated with aging research; evidence remains limited and contested.
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13 · 1990s–2000s
AOD-9604
Australia
Modified growth-hormone fragment investigated for obesity without an FDA-approved use.
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14 · 1977
DSIP
Switzerland
Delta sleep-inducing peptide with inconsistent evidence and uncertain physiological significance.
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15 · 1995
LL-37
Human innate-immunity research
Human cathelicidin peptide studied for antimicrobial and immune effects; therapeutic use remains experimental.
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