01 · 1953 synthesis
Oxytocin
New York, USA
Bonding, childbirth, and lactation signaling.
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The six biological messengers at the founding
02 · 1950s structure
Vasopressin
New York, USA
Water balance and vascular tone.
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03 · 1948
Bradykinin
São Paulo, Brazil
Pain, inflammation, and vascular signaling.
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04 · 1939 lineage
Angiotensin II
Argentina + USA
Pressure and fluid-balance signaling.
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05 · 1962
Calcitonin
Vancouver, Canada
Calcium and bone-resorption signaling.
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06 · 1969 structure
TRH
United States
The first hypothalamic releasing-hormone structure.
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